MolNFT v2 · #121637 · protein
HIV Integrase Catalytic Domain containing F185K mutation complexed with GSK0002
5HRN: “HIV Integrase Catalytic Domain containing F185K mutation complexed with GSK0002”. X-ray diffraction at 1.75, 2 ligands (65P, SO4). MolNFT v2 #121637 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5HRN
- Type
- protein
- Length
- 148 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.75
- Source
- Human immunodeficiency virus 1
- UniProt
- P04585
- Ligands
- 65P, SO4
Structure
x-ray diffraction · resolution 1.75 · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 148 | — | P04585 |
Ligands and binding sites
- 65P · (2S)-tert-butoxy[1-(3,4-difluorobenzyl)-6-methyl-4-(5-methyl-3,4-dihydro-2H-chromen-6-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]acetic acid · ligand · chains A
- SO4 · Sulfate ion · ion · chains A
- CAC · Cacodylate ion · additive · 2 copies · chains A
- EDO · 1,2-ethanediol · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5HRN · HIV integrase catalytic domain containing F185K mutation complexed with GSK0002 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P04585
- Elsewhere: RCSB PDB 5HRN · PDBe 5HRN · UniProt P04585
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