MolNFT v2 · #119912 · protein
Direct Observation of Active-site Protonation States in a Class A beta lactamase with a monobactam substrate
5G18: “Direct Observation of Active-site Protonation States in a Class A beta lactamase with a monobactam substrate”. X-ray diffraction at 1.1, 2 ligands (AZR, SO4). MolNFT v2 #119912 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 5G18
- Type
- protein
- Length
- 261 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.1
- Source
- ESCHERICHIA COLI
- UniProt
- E1ANH6
- Ligands
- AZR, SO4
Structure
x-ray diffraction · resolution 1.1 · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 261 | — | E1ANH6 |
Ligands and binding sites
- AZR · 2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl)-2-oxo-2-{[(2S, 3S)-1-oxo-3-(sulfoamino)butan-2-yl]amino}ethylidene]amino}oxy)-2-methylpropanoic acid · ligand · chains A
- SO4 · Sulfate ion · ion · 5 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5G18 · Direct observation of active-site protonation states in a class a beta lactamase with a… · the same entry in another collection · chain A against A, TM-score 1.00
- E1ANH6 · AlphaFold monomer V2.0 prediction for beta-lactamase ctx-M-97 (E1ANH6) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt E1ANH6
- Elsewhere: RCSB PDB 5G18 · PDBe 5G18 · UniProt E1ANH6
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