MolNFT v2 · #119639 · protein

Crystal structure of Trypanosoma cruzi macrodomain

5FSZ: “Crystal structure of Trypanosoma cruzi macrodomain”. X-ray diffraction at 2, 1 pocket (best druggability 0.56). MolNFT v2 #119639 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5FSZ
Type: protein
Length: 245 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 2
Source: TRYPANOSOMA CRUZI
Molecule: Macrodomain
UniProt: Q4DQ03
Pockets: 1 · best druggability 0.56

Structure

x-ray diffraction · resolution 2 · 1 distinct chain · 42% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Macrodomain	protein	245	42% helix, 13% strand	Q4DQ03

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	260	0.56	0.78	34	empty

Compared structures

5FSZ · Crystal structure of trypanosoma cruzi macrodomain · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q4DQ03
Elsewhere: RCSB PDB 5FSZ · PDBe 5FSZ · UniProt Q4DQ03

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