MolNFT v2 · #118785 · protein

X-ray crystal structure of a thiolase from Escherichia coli at 1.8 A resolution

5F38: “X-ray crystal structure of a thiolase from Escherichia coli at 1.8 A resolution”. X-ray diffraction at 1.9, 2 ligands (5UG, COZ). MolNFT v2 #118785 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5F38
Type: protein
Length: 1,548 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 1.9
Source: Escherichia coli K-12
UniProt: P76461
Ligands: 5UG, COZ

Structure

x-ray diffraction · resolution 1.9 · 4 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
B	—	protein	391	—	P76461
A	—	protein	371	—	P76461
D	—	protein	394	—	P76461
C	—	protein	392	—	P76461

Ligands and binding sites

5UG · [(3~{S})-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-4-[[3-oxidanylidene-3-(2-sulfanylethylamino)propyl]amino]butyl] phosphono hydrogen phosphate · ligand · 2 copies · chains A, D, C
COZ · Coenzyme A · ligand · chains B, C
EDO · 1,2-ethanediol · additive · 31 copies · chains B, A, D, C

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

5F38 · X-ray crystal structure of a thiolase from escherichia COLI at 1.8 a resolution · the same entry in another collection · chain D against D, TM-score 1.00
P76461 · AlphaFold monomer V2.0 prediction for acetyl-CoA acetyltransferase (P76461) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P76461
Elsewhere: RCSB PDB 5F38 · PDBe 5F38 · UniProt P76461

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