MolNFT v2 · #116621 · protein
Crystal Structure of Human KEAP1 BTB Domain in Complex with Small Molecule TX64014
5DAD: “Crystal Structure of Human KEAP1 BTB Domain in Complex with Small Molecule TX64014”. X-ray diffraction at 2.61, 1 ligand (TX6). MolNFT v2 #116621 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5DAD
- Type
- protein
- Length
- 123 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.61
- Source
- Homo sapiens
- UniProt
- Q14145
- Ligands
- TX6
Structure
x-ray diffraction · resolution 2.61 · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 123 | — | Q14145 |
Ligands and binding sites
- TX6 · (6aS,7S,10aS)-8-hydroxy-4-methoxy-2,7,10a-trimethyl-5,6,6a,7,10,10a-hexahydrobenzo[h]quinazoline-9-carbonitrile · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5DAD · Crystal structure of human KEAP1 btb domain in complex with small molecule TX64014 · the same entry in another collection · chain A against A, TM-score 1.00
- Q14145 · AlphaFold monomer V2.0 prediction for kelch-like ech-associated protein 1 (Q14145) · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q14145
- Elsewhere: RCSB PDB 5DAD · PDBe 5DAD · UniProt Q14145
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