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MolNFT v2 · #107081 · protein

Crystal structure of the C-terminal domain of an unknown protein from Leishmania infantum

4TYZ · Uncharacterized protein: “Crystal structure of the C-terminal domain of an unknown protein from Leishmania infantum”. X-ray diffraction at 1.6, 1 pocket (best druggability 0.56). MolNFT v2 #107081 on GenesisL1: 3D structure, binding…

PDB
4TYZ
Type
protein
Length
218 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v2 / PDB Bank
Contract
0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner
0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution
1.6
Source
Leishmania infantum
Molecule
Uncharacterized protein
UniProt
A4I5U9
Pockets
1 · best druggability 0.56

Structure

x-ray diffraction · resolution 1.6 · 1 distinct chain · 24% helix, 41% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A, BUncharacterized proteinprotein10924% helix, 41% strandA4I5U9

Ligands and binding sites

  • EDO · 1,2-ethanediol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12250.560.7834empty

Interfaces

1 interface between chains.

  • A–B · 213 Ų buried · 0 hydrogen bonds · protein-protein

Compared structures

  • 4TYZ · Crystal structure of the C-terminal domain of an unknown protein from leishmania infantum · the same entry in another collection · chain A against A, TM-score 1.00

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