MolNFT v1 · #99979 · protein
Crystal structure of the double mutant (S112A, H303A) of B.ANTHRACIS mycrocine immunity protein (mccf)
4MJX · Microcin immunity protein mccf: “Crystal structure of the double mutant (S112A, H303A) of B.ANTHRACIS mycrocine immunity protein (mccf)”. X-ray diffraction, 4 pockets (best druggability 0.59). MolNFT v1 #99979 on GenesisL1: 3D…
- PDB
- 4MJX
- Type
- protein
- Length
- 669 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Microcin immunity protein mccf
- UniProt
- Q81RT8
- Pockets
- 4 · best druggability 0.59
Structure
x-ray diffraction · 2 distinct chains · 31% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Microcin immunity protein mccf | protein | 333 | 32% helix, 23% strand | Q81RT8 |
| B | Microcin immunity protein mccf | protein | 336 | 31% helix, 22% strand | Q81RT8 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 315 | 0.59 | 0.77 | 35 | EDO |
| 2 | 322 | 0.59 | 0.77 | 44 | GOL |
| 3 | 75 | 0.37 | 0.77 | 18 | empty |
| 4 | 69 | 0.36 | 0.77 | 18 | empty |
Interfaces
1 interface between chains.
- A–B · 1832 Ų buried · 41 hydrogen bonds · protein-protein
Compared structures
- 4MJX · Crystal structure of the double mutant (S112A, H303A) of B.anthracis mycrocine immunity… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q81RT8
- Elsewhere: RCSB PDB 4MJX · PDBe 4MJX · UniProt Q81RT8
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.