MolNFT v1 · #99890 · protein
The crystal structure of the monomeric reverse transcriptase from moloney murine leukemia virus
4MH8 · Reverse TRANSCRIPTASE/RIBONUCLEASE H P80: “The crystal structure of the monomeric reverse transcriptase from moloney murine leukemia virus”. X-ray diffraction, 4 pockets (best druggability 0.51). MolNFT v1 #99890 on GenesisL1: 3D…
- PDB
- 4MH8
- Type
- protein
- Length
- 453 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Reverse TRANSCRIPTASE/RIBONUCLEASE H P80
- EC
- 2.7.7.49, 2.7.7.7, 3.1.26.4
- UniProt
- P03355
- Pockets
- 4 · best druggability 0.51
Structure
x-ray diffraction · 1 distinct chain · 31% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Reverse TRANSCRIPTASE/RIBONUCLEASE H P80 (EC 2.7.7.49, 2.7.7.7, 3.1.26.4) | protein | 453 | 31% helix, 23% strand | P03355 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 201 | 0.51 | 0.76 | 28 | empty |
| 2 | 85 | 0.41 | 0.78 | 18 | empty |
| 3 | 63 | 0.38 | 0.79 | 12 | empty |
| 4 | 76 | 0.30 | 0.73 | 19 | empty |
Compared structures
- 4MH8 · The crystal structure of the monomeric reverse transcriptase from moloney murine leukemia… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03355
- Elsewhere: RCSB PDB 4MH8 · PDBe 4MH8 · UniProt P03355
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.