MolNFT v1 · #99839 · protein
Crystal structure of M121G azurin
4MFH: “Crystal structure of M121G azurin”. X-ray diffraction, 1 ligand (CU), 4 pockets (best druggability 0.63). MolNFT v1 #99839 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4MFH
- Type
- protein
- Length
- 384 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Azurin
- UniProt
- P00282
- Ligands
- CU
- Pockets
- 4 · best druggability 0.63
Structure
x-ray diffraction · 1 distinct chain · 19% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C | Azurin | protein | 128 | 19% helix, 32% strand | P00282 |
Ligands and binding sites
- CU · Copper (II) ion · metal · 6 copies · chains A, B, C
- TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol · additive · 3 copies · chains A, B, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 113 | 0.63 | 0.88 | 17 | CU, TRS |
| 2 | 147 | 0.63 | 0.86 | 29 | CU, TRS |
| 3 | 61 | 0.30 | 0.75 | 18 | empty |
| 4 | 58 | 0.29 | 0.75 | 17 | empty |
Interfaces
2 interfaces between chains.
- A–C · 402 Ų buried · 3 hydrogen bonds · protein-protein
- A–B · 401 Ų buried · 3 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 3 disulfide (disulfide).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00282
- Elsewhere: RCSB PDB 4MFH · PDBe 4MFH · UniProt P00282
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.