MolNFT v1 · #99804 · RNA
In vitro evolved glms ribozyme triple mutant, magnesium ion complex
4MEG · Glms triple mutant ribozyme: “In vitro evolved glms ribozyme triple mutant, magnesium ion complex”. X-ray diffraction, 1 ligand (MG), 4 pockets (best druggability 0.73). MolNFT v1 #99804 on GenesisL1: 3D structure, binding sites and…
- PDB
- 4MEG
- Type
- RNA
- Length
- 137 nucleotides
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glms triple mutant ribozyme; (121-mer) ribozyme
- Ligands
- MG
- Pockets
- 4 · best druggability 0.73
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Glms triple mutant ribozyme | rna | 16 | — | — |
| B | (121-mer) ribozyme | rna | 121 | — | — |
Ligands and binding sites
- MG · Magnesium ion · metal · 16 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 600 | 0.73 | 0.81 | 44 | MG |
| 2 | 872 | 0.68 | 0.75 | 57 | MG |
| 3 | 292 | 0.68 | 0.84 | 18 | MG |
| 4 | 273 | 0.50 | 0.75 | 21 | MG |
Interfaces
1 interface between chains.
- A–B · 1295 Ų buried · 82 hydrogen bonds · nucleic-nucleic
Compared structures
- 4MEG · In vitro evolved glmS ribozyme triple mutant, magnesium ion complex · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 4MEG · PDBe 4MEG
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