MolNFT v1 · #9980 · protein

Crystal structure of the nucleotide bond conformation of phoq kinase domain

1ID0 · Phoq histidine kinase: “Crystal structure of the nucleotide bond conformation of phoq kinase domain”. X-ray diffraction, 2 ligands (ANP, MG), 1 pocket (best druggability 0.52). MolNFT v1 #9980 on GenesisL1: 3D structure, binding…

PDB: 1ID0
Type: protein
Length: 146 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Phoq histidine kinase
EC: 2.7.1.37
UniProt: P23837
Ligands: ANP, MG
Pockets: 1 · best druggability 0.52

Structure

x-ray diffraction · 1 distinct chain · 34% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Phoq histidine kinase (EC 2.7.1.37)	protein	146	34% helix, 27% strand	P23837

Ligands and binding sites

ANP · Phosphoaminophosphonic acid-adenylate ester · ligand · chains A
MG · Magnesium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	196	0.52	0.77	26	MG, ANP

Compared structures

1ID0 · Crystal structure of the nucleotide bond conformation of phoq kinase domain · the same entry in another collection · chain A against A, TM-score 1.00
P23837 · AlphaFold monomer V2.0 prediction for sensor protein phoq (P23837) · a predicted model of the same protein · chain A against A, TM-score 0.92

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P23837
Elsewhere: RCSB PDB 1ID0 · PDBe 1ID0 · UniProt P23837

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