MolNFT v1 · #99525 · protein
Crystal structure of macrolide glycosyltransferases oled
4M60 · Oleandomycin glycosyltransferase: “Crystal structure of macrolide glycosyltransferases oled”. X-ray diffraction, 1 ligand (NA), 1 pocket (best druggability 0.73). MolNFT v1 #99525 on GenesisL1: 3D structure, binding sites and…
- PDB
- 4M60
- Type
- protein
- Length
- 376 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Oleandomycin glycosyltransferase
- UniProt
- Q3HTL6
- Ligands
- NA
- Pockets
- 1 · best druggability 0.73
Structure
x-ray diffraction · 1 distinct chain · 46% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Oleandomycin glycosyltransferase | protein | 376 | 46% helix, 15% strand | Q3HTL6 |
Ligands and binding sites
- NA · Sodium ion · metal · chains A
- EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 856 | 0.73 | 0.78 | 80 | empty |
Modifications
Observed in the structure: 5 modified (engineered).
Compared structures
- 4M60 · Crystal structure of macrolide glycosyltransferases OleD · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q3HTL6
- Elsewhere: RCSB PDB 4M60 · PDBe 4M60 · UniProt Q3HTL6
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