MolNFT v1 · #99318 · protein
Complex of iqcg and CA2+-free cam
4LZX · Calmodulin: “Complex of iqcg and CA2+-free cam”. X-ray diffraction, 1 ligand (SO4), 2 pockets (best druggability 0.56). MolNFT v1 #99318 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4LZX
- Type
- protein
- Length
- 182 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Calmodulin; Iq domain-containing protein G
- UniProt
- P62158, Q9H095
- Ligands
- SO4
- Pockets
- 2 · best druggability 0.56
Structure
x-ray diffraction · 2 distinct chains · 60% helix, 7% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Calmodulin | protein | 145 | 59% helix, 8% strand | P62158 |
| B | Iq domain-containing protein G | protein | 37 | 62% helix, 0% strand | Q9H095 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 350 | 0.56 | 0.75 | 34 | empty |
| 2 | 59 | 0.27 | 0.73 | 14 | empty |
Interfaces
1 interface between chains.
- A–B · 1462 Ų buried · 17 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P62158
- Every structure of UniProt Q9H095
- Elsewhere: RCSB PDB 4LZX · PDBe 4LZX · UniProt P62158 · UniProt Q9H095
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