MolNFT v1 · #99177 · protein

Crystal structure of IFT81 N-terminal domain

4LVR · Intraflagellar transport protein 81: “Crystal structure of IFT81 N-terminal domain”. X-ray diffraction, 2 pockets (best druggability 0.32). MolNFT v1 #99177 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4LVR
Type: protein
Length: 120 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Intraflagellar transport protein 81
UniProt: Q68RJ5
Pockets: 2 · best druggability 0.32

Structure

x-ray diffraction · 1 distinct chain · 62% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Intraflagellar transport protein 81	protein	120	62% helix, 0% strand	Q68RJ5

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	60	0.32	0.75	12	empty
2	52	0.29	0.75	12	empty

Compared structures

4LVR · Crystal structure of IFT81 N-terminal domain · the same entry in another collection · chain A against A, TM-score 1.00
Q68RJ5 · AlphaFold monomer V2.0 prediction for intraflagellar transport protein 81 (Q68RJ5) · a predicted model of the same protein · chain A against A, TM-score 0.89

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q68RJ5
Elsewhere: RCSB PDB 4LVR · PDBe 4LVR · UniProt Q68RJ5

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