MolNFT v1 · #99141 · protein
Crystal structure of zebrafish interphotoreceptor retinoid-binding protein (irbp) module 1
4LUR · Interphotoreceptor retinoid-binding PROTEIN(IRBP): “Crystal structure of zebrafish interphotoreceptor retinoid-binding protein (irbp) module 1”. X-ray diffraction, 1 ligand (OLA), 3 pockets (best druggability 0.84). MolNFT v1 #99141…
- PDB
- 4LUR
- Type
- protein
- Length
- 309 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Interphotoreceptor retinoid-binding PROTEIN(IRBP)
- UniProt
- F1Q9N9
- Ligands
- OLA
- Pockets
- 3 · best druggability 0.84
Structure
x-ray diffraction · 1 distinct chain · 39% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Interphotoreceptor retinoid-binding PROTEIN(IRBP) | protein | 309 | 39% helix, 21% strand | F1Q9N9 |
Ligands and binding sites
- OLA · Oleic acid · ligand · chains A
- GOL · Glycerol · additive · 3 copies · chains A
- EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 280 | 0.84 | 0.94 | 29 | empty |
| 2 | 150 | 0.69 | 0.89 | 21 | OLA |
| 3 | 106 | 0.36 | 0.74 | 18 | empty |
Modifications
Observed in the structure: 11 modified (engineered).
Compared structures
- 4LUR · Crystal Structure of Zebrafish Interphotoreceptor Retinoid-Binding Protein (IRBP) Module 1 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt F1Q9N9
- Elsewhere: RCSB PDB 4LUR · PDBe 4LUR · UniProt F1Q9N9
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