MolNFT v1 · #99085 · protein

Hewl co-crystallized with carboplatin in non-nacl conditions: crystal 2 processed using the eval software package

4LT2 · Lysozyme C: “Hewl co-crystallized with carboplatin in non-nacl conditions: crystal 2 processed using the eval software…”. X-ray diffraction, 1 ligand (QPT), 1 pocket (best druggability 0.31). MolNFT v1 #99085 on GenesisL1: 3D…

PDB: 4LT2
Type: protein
Length: 129 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Lysozyme C
EC: 3.2.1.17
UniProt: P00698
Ligands: QPT
Pockets: 1 · best druggability 0.31

Structure

x-ray diffraction · 1 distinct chain · 41% helix, 11% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Lysozyme C (EC 3.2.1.17)	protein	129	41% helix, 11% strand	P00698

Ligands and binding sites

QPT · carboplatin · ligand · 2 copies · chains A
DMS · Dimethyl sulfoxide · additive · 5 copies · chains A
MPD · (4S)-2-methyl-2,4-pentanediol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	54	0.31	0.76	14	DMS

Modifications

Observed in the structure: 4 disulfide (disulfide).

Compared structures

4LT2 · HEWL co-crystallized with Carboplatin in non-NaCl conditions: crystal 2 processed using… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P00698
Elsewhere: RCSB PDB 4LT2 · PDBe 4LT2 · UniProt P00698

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