MolNFT v1 · #98758 · protein

Crystal structure of chorismate synthase from acinetobacter baumannii at 3.15A resolution

4LJ2: “Crystal structure of chorismate synthase from acinetobacter baumannii at 3.15A resolution”. X-ray diffraction, 7 pockets (best druggability 0.78). MolNFT v1 #98758 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4LJ2
Type: protein
Length: 646 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Chorismate synthase
EC: 4.2.3.5
UniProt: D0C7F3
Pockets: 7 · best druggability 0.78

Structure

x-ray diffraction · 2 distinct chains · 27% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Chorismate synthase (EC 4.2.3.5)	protein	322	26% helix, 21% strand	D0C7F3
B	Chorismate synthase (EC 4.2.3.5)	protein	324	28% helix, 21% strand	D0C7F3

Pockets

7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	920	0.78	0.81	96	empty
2	1091	0.76	0.78	103	empty
3	282	0.66	0.83	35	empty
4	160	0.49	0.78	23	empty
5	150	0.40	0.73	24	empty

Interfaces

1 interface between chains.

A–B · 2522 Å² buried · 38 hydrogen bonds · protein-protein

Compared structures

4LJ2 · Crystal structure of chorismate synthase from Acinetobacter baumannii at 3.15A resolution · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt D0C7F3
Elsewhere: RCSB PDB 4LJ2 · PDBe 4LJ2 · UniProt D0C7F3

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