MolNFT v1 · #98675 · protein
N-terminal truncated nlec structure
4LGI · Uncharacterized protein: “N-terminal truncated nlec structure”. X-ray diffraction, 9 pockets (best druggability 0.79). MolNFT v1 #98675 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4LGI
- Type
- protein
- Length
- 832 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Uncharacterized protein
- UniProt
- Q8X834
- Pockets
- 9 · best druggability 0.79
Structure
x-ray diffraction · 4 distinct chains · 55% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Uncharacterized protein | protein | 212 | 57% helix, 8% strand | Q8X834 |
| B | Uncharacterized protein | protein | 206 | 54% helix, 8% strand | Q8X834 |
| C | Uncharacterized protein | protein | 208 | 56% helix, 8% strand | Q8X834 |
| D | Uncharacterized protein | protein | 206 | 54% helix, 8% strand | Q8X834 |
Pockets
9 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 775 | 0.79 | 0.83 | 72 | empty |
| 2 | 810 | 0.79 | 0.82 | 77 | empty |
| 3 | 187 | 0.44 | 0.74 | 27 | empty |
| 4 | 132 | 0.43 | 0.76 | 24 | empty |
| 5 | 142 | 0.42 | 0.75 | 19 | empty |
Interfaces
3 interfaces between chains.
- B–C · 919 Ų buried · 13 hydrogen bonds · protein-protein
- A–D · 907 Ų buried · 11 hydrogen bonds · protein-protein
- A–B · 170 Ų buried · 0 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 12 modified (engineered).
Compared structures
- 4LGI · N-terminal truncated NleC structure · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8X834
- Elsewhere: RCSB PDB 4LGI · PDBe 4LGI · UniProt Q8X834
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