MolNFT v1 · #97864 · protein
Crystal structure of drosophila wntd N-terminal domain-linker (residues 31-240)
4KRR · Wnt inhibitor of dorsal protein: “Crystal structure of drosophila wntd N-terminal domain-linker (residues 31-240)”. X-ray diffraction, 1 ligand (NA), 2 pockets (best druggability 0.59). MolNFT v1 #97864 on GenesisL1: 3D structure…
- PDB
- 4KRR
- Type
- protein
- Length
- 194 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Wnt inhibitor of dorsal protein
- UniProt
- Q9VFX1
- Ligands
- NA
- Pockets
- 2 · best druggability 0.59
Structure
x-ray diffraction · 1 distinct chain · 46% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Wnt inhibitor of dorsal protein | protein | 194 | 46% helix, 10% strand | Q9VFX1 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 146 | 0.59 | 0.83 | 25 | GOL |
| 2 | 134 | 0.45 | 0.77 | 28 | GOL |
Modifications
Observed in the structure: 5 disulfide (disulfide).
Compared structures
- 4KRR · Crystal structure of Drosophila WntD N-terminal domain-linker (residues 31-240) · the same entry in another collection · chain A against A, TM-score 1.00
- Q9VFX1 · AlphaFold monomer V2.0 prediction for wnt inhibitor of dorsal protein (Q9VFX1) · a predicted model of the same protein · chain A against A, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9VFX1
- Elsewhere: RCSB PDB 4KRR · PDBe 4KRR · UniProt Q9VFX1
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