MolNFT v1 · #97719 · protein
Structural and functional characterization of pseudomonas aeruginosa algx
4KNC · Alginate biosynthesis protein algx: “Structural and functional characterization of pseudomonas aeruginosa algx”. X-ray diffraction, 4 pockets (best druggability 0.63). MolNFT v1 #97719 on GenesisL1: 3D structure, binding sites and…
- PDB
- 4KNC
- Type
- protein
- Length
- 829 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Alginate biosynthesis protein algx
- UniProt
- Q51372
- Pockets
- 4 · best druggability 0.63
Structure
x-ray diffraction · 2 distinct chains · 32% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | Alginate biosynthesis protein algx | protein | 419 | 33% helix, 26% strand | Q51372 |
| A | Alginate biosynthesis protein algx | protein | 410 | 32% helix, 26% strand | Q51372 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 96 | 0.63 | 0.89 | 24 | empty |
| 2 | 105 | 0.55 | 0.84 | 29 | empty |
| 3 | 197 | 0.42 | 0.72 | 31 | empty |
| 4 | 97 | 0.38 | 0.76 | 19 | empty |
Interfaces
1 interface between chains.
- B–A · 577 Ų buried · 3 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 disulfide (disulfide).
Compared structures
- 4KNC · Structural and functional characterization of Pseudomonas aeruginosa AlgX · the same entry in another collection · chain B against B, TM-score 1.00
- Q51372 · AlphaFold monomer V2.0 prediction for alginate biosynthesis protein algx (Q51372) · a predicted model of the same protein · chain B against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q51372
- Elsewhere: RCSB PDB 4KNC · PDBe 4KNC · UniProt Q51372
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