MolNFT v1 · #97453 · protein
Crystal structure of mbp fused human SPLUNC1
4KEG · Maltose-binding PERIPLASMIC/PALATE lung and nasal…: “Crystal structure of mbp fused human SPLUNC1”. X-ray diffraction, 1 ligand (MG), 4 pockets (best druggability 0.61). MolNFT v1 #97453 on GenesisL1: 3D structure, binding sites and…
- PDB
- 4KEG
- Type
- protein
- Length
- 535 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Maltose-binding PERIPLASMIC/PALATE lung and nasal epithelium clone fusion protein
- UniProt
- P0AEX9, Q9NP55
- Ligands
- MG
- Pockets
- 4 · best druggability 0.61
Structure
x-ray diffraction · 1 distinct chain · 42% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Maltose-binding PERIPLASMIC/PALATE lung and nasal epithelium clone fusion protein | protein | 535 | 42% helix, 23% strand | P0AEX9, Q9NP55 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 121 | 0.61 | 0.85 | 23 | empty |
| 2 | 371 | 0.59 | 0.76 | 45 | empty |
| 3 | 328 | 0.53 | 0.74 | 32 | empty |
| 4 | 73 | 0.31 | 0.73 | 16 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0AEX9
- Every structure of UniProt Q9NP55
- Elsewhere: RCSB PDB 4KEG · PDBe 4KEG · UniProt P0AEX9 · UniProt Q9NP55
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.