MolNFT v1 · #96943 · protein
Crystal structure of FKBP25 from plasmodium vivax
4JYS · Peptidyl-prolyl cis-trans isomerase: “Crystal structure of FKBP25 from plasmodium vivax”. X-ray diffraction, 1 ligand (CL), 2 pockets (best druggability 0.54). MolNFT v1 #96943 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 4JYS
- Type
- protein
- Length
- 246 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Peptidyl-prolyl cis-trans isomerase
- UniProt
- A5JZC2
- Ligands
- CL
- Pockets
- 2 · best druggability 0.54
Structure
x-ray diffraction · 2 distinct chains · 11% helix, 36% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Peptidyl-prolyl cis-trans isomerase | protein | 132 | 13% helix, 33% strand | A5JZC2 |
| B | Peptidyl-prolyl cis-trans isomerase | protein | 114 | 8% helix, 39% strand | A5JZC2 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 317 | 0.54 | 0.75 | 36 | empty |
| 2 | 55 | 0.27 | 0.73 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 177 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 4JYS · Crystal structure of FKBP25 from Plasmodium Vivax · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A5JZC2
- Elsewhere: RCSB PDB 4JYS · PDBe 4JYS · UniProt A5JZC2
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.