MolNFT v1 · #96543 · protein
Complexe of arno SEC7 domain with the protein-protein interaction inhibitor N-(4-hydroxy-2,6-dimethylphenyl)-4- methoxybenzenesulfonamide
4JMO · Cytohesin-2: “Complexe of arno SEC7 domain with the protein-protein interaction inhibitor…”. X-ray diffraction, 1 ligand (JAF), 1 pocket (best druggability 0.43). MolNFT v1 #96543 on GenesisL1: 3D structure, binding sites and…
- PDB
- 4JMO
- Type
- protein
- Length
- 193 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cytohesin-2
- UniProt
- Q99418
- Ligands
- JAF
- Pockets
- 1 · best druggability 0.43
Structure
x-ray diffraction · 1 distinct chain · 66% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cytohesin-2 | protein | 193 | 66% helix, 1% strand | Q99418 |
Ligands and binding sites
- JAF · N-(4-hydroxy-2,6-dimethylphenyl)-4-methoxybenzenesulfonamide · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 93 | 0.43 | 0.78 | 14 | JAF |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q99418
- Elsewhere: RCSB PDB 4JMO · PDBe 4JMO · UniProt Q99418
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