MolNFT v1 · #96004 · protein
Crystal structure of beta'-COP/P25 complex
4J73 · Coatomer subunit beta': “Crystal structure of beta'-COP/P25 complex”. X-ray diffraction, 1 pocket (best druggability 0.79). MolNFT v1 #96004 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4J73
- Type
- protein
- Length
- 301 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Coatomer subunit beta'; Transmembrane EMP24 domain-containing protein 9
- UniProt
- P41811, Q3T133
- Pockets
- 1 · best druggability 0.79
Structure
x-ray diffraction · 2 distinct chains · 2% helix, 54% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Coatomer subunit beta' | protein | 295 | 1% helix, 55% strand | P41811 |
| B | Transmembrane EMP24 domain-containing protein 9 | protein | 6 | 67% helix, 0% strand | Q3T133 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 702 | 0.79 | 0.83 | 53 | empty |
Interfaces
1 interface between chains.
- A–B · 385 Ų buried · 13 hydrogen bonds · protein-protein
Compared structures
- 4J73 · Crystal structure of beta'-COP/p25 complex · the same entry in another collection · chain A against A, TM-score 1.00
- P41811 · AlphaFold monomer V2.0 prediction for coatomer subunit beta' (P41811) · a predicted model of the same protein · chain A against A, TM-score 1.00
- Q3T133 · AlphaFold monomer V2.0 prediction for transmembrane EMP24 domain- containing protein 9… · a predicted model of the same protein · chain B against A, TM-score 0.78
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P41811
- Every structure of UniProt Q3T133
- Elsewhere: RCSB PDB 4J73 · PDBe 4J73 · UniProt P41811 · UniProt Q3T133
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