MolNFT v1 · #9528 · protein
C4ADG fragment of human complement factor C4A
1HZF: “C4ADG fragment of human complement factor C4A”. X-ray diffraction, 2 pockets (best druggability 0.40). MolNFT v1 #9528 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1HZF
- Type
- protein
- Length
- 302 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Complement factor C4A
- EC
- 3.4.21.43
- UniProt
- P01028
- Pockets
- 2 · best druggability 0.40
Structure
x-ray diffraction · 1 distinct chain · 64% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Complement factor C4A (EC 3.4.21.43) | protein | 302 | 64% helix, 3% strand | P01028 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 104 | 0.40 | 0.76 | 18 | empty |
| 2 | 70 | 0.39 | 0.79 | 17 | empty |
Modifications
Observed in the structure: 5 modified (engineered).
Compared structures
- 1HZF · C4ADG fragment of human complement factor C4A · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P01028
- Elsewhere: RCSB PDB 1HZF · PDBe 1HZF · UniProt P01028
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