MolNFT v1 · #95273 · protein
Crystal structure of an H329A mutant of P. aeruginosa PMM/PGM
4IL8 · PHOSPHOMANNOMUTASE/PHOSPHOGLUCOMUTASE: “Crystal structure of an H329A mutant of P. aeruginosa PMM/PGM”. X-ray diffraction, 1 ligand (MG), 3 pockets (best druggability 0.74). MolNFT v1 #95273 on GenesisL1: 3D structure, binding sites…
- PDB
- 4IL8
- Type
- protein
- Length
- 459 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- PHOSPHOMANNOMUTASE/PHOSPHOGLUCOMUTASE
- EC
- 5.4.2.2, 5.4.2.8
- UniProt
- P26276
- Ligands
- MG
- Pockets
- 3 · best druggability 0.74
Structure
x-ray diffraction · 1 distinct chain · 38% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | PHOSPHOMANNOMUTASE/PHOSPHOGLUCOMUTASE (EC 5.4.2.2, 5.4.2.8) | protein | 459 | 38% helix, 25% strand | P26276 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 737 | 0.74 | 0.80 | 64 | empty |
| 2 | 108 | 0.54 | 0.83 | 19 | GOL |
| 3 | 67 | 0.30 | 0.74 | 15 | empty |
Modifications
Observed in the structure: 1 modified (phosphorylation).
Compared structures
- 4IL8 · Crystal structure of an H329A mutant of p. aeruginosa PMM/PGM · the same entry in another collection · chain A against A, TM-score 1.00
- P26276 · AlphaFold monomer V2.0 prediction for PHOSPHOMANNOMUTASE/PHOSPHOGLUCOMUTASE (P26276) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P26276
- Elsewhere: RCSB PDB 4IL8 · PDBe 4IL8 · UniProt P26276
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.