MolNFT v1 · #95213 · protein
Structure of transcription factor DKSA2 from pseudomonas aeruginosa
4IJJ · Putative C4-type zinc finger protein, DKSA/TRAR family: “Structure of transcription factor DKSA2 from pseudomonas aeruginosa”. X-ray diffraction, 1 ligand (SO4), 4 pockets (best druggability 0.81). MolNFT v1 #95213 on GenesisL1: 3D…
- PDB
- 4IJJ
- Type
- protein
- Length
- 388 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative C4-type zinc finger protein, DKSA/TRAR family
- UniProt
- Q02DH2
- Ligands
- SO4
- Pockets
- 4 · best druggability 0.81
Structure
x-ray diffraction · 2 distinct chains · 65% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C | Putative C4-type zinc finger protein, DKSA/TRAR family | protein | 129 | 64% helix, 2% strand | Q02DH2 |
| B | Putative C4-type zinc finger protein, DKSA/TRAR family | protein | 130 | 66% helix, 2% strand | Q02DH2 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 3 copies · chains A, B, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1030 | 0.81 | 0.82 | 119 | SO4 |
| 2 | 141 | 0.45 | 0.76 | 13 | empty |
| 3 | 66 | 0.30 | 0.74 | 16 | empty |
| 4 | 51 | 0.26 | 0.74 | 10 | empty |
Interfaces
3 interfaces between chains.
- B–C · 684 Ų buried · 11 hydrogen bonds · protein-protein
- A–C · 679 Ų buried · 12 hydrogen bonds · protein-protein
- A–B · 659 Ų buried · 14 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 4IJJ · Structure of transcription factor DksA2 from Pseudomonas aeruginosa · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q02DH2
- Elsewhere: RCSB PDB 4IJJ · PDBe 4IJJ · UniProt Q02DH2
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