MolNFT v1 · #95165 · protein

Archaellum assembly ATPase flai

4II7 · Flai ATPase: “Archaellum assembly ATPase flai”. X-ray diffraction, 20 pockets (best druggability 0.82). MolNFT v1 #95165 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4II7
Type: protein
Length: 2,012 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Flai ATPase
EC: 3.6.1.4
UniProt: Q4J9L0
Pockets: 20 · best druggability 0.82

Structure

x-ray diffraction · 4 distinct chains · 35% helix, 24% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Flai ATPase (EC 3.6.1.4)	protein	504	35% helix, 24% strand	Q4J9L0
B	Flai ATPase (EC 3.6.1.4)	protein	500	36% helix, 24% strand	Q4J9L0
C	Flai ATPase (EC 3.6.1.4)	protein	510	35% helix, 25% strand	Q4J9L0
D	Flai ATPase (EC 3.6.1.4)	protein	498	35% helix, 24% strand	Q4J9L0

Pockets

20 pockets found on a 1 Å grid, 9 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	872	0.82	0.84	95	empty
2	494	0.75	0.84	57	empty
3	286	0.70	0.85	34	empty
4	504	0.64	0.76	61	empty
5	362	0.57	0.75	36	empty

Interfaces

4 interfaces between chains.

A–B · 1762 Å² buried · 19 hydrogen bonds · protein-protein
C–D · 1718 Å² buried · 11 hydrogen bonds · protein-protein
B–D · 342 Å² buried · 1 hydrogen bond · protein-protein
B–C · 81 Å² buried · 0 hydrogen bonds · protein-protein

Compared structures

4II7 · Archaellum Assembly ATPase FlaI · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q4J9L0
Elsewhere: RCSB PDB 4II7 · PDBe 4II7 · UniProt Q4J9L0

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