MolNFT v1 · #9514 · DNA

NMR structure of the 2-amino-1-methyl-6-PHENYLIMIDAZO[4,5-B]PYRIDINE (phip) C8-deoxyguanosine adduct in duplex DNA

1HZ0 · DNA (5'-D(*CP*CP*AP*TP*CP*GP*CP*TP*AP*CP*C)-3'): “NMR structure of the 2-amino-1-methyl-6-PHENYLIMIDAZO[4,5-B]PYRIDINE (phip) C8-deoxyguanosine adduct in…”. Solution nmr, 1 ligand (PIQ). MolNFT v1 #9514 on GenesisL1: 3D structure…

PDB: 1HZ0
Type: DNA
Length: 22 nucleotides
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: DNA (5'-D(*CP*CP*AP*TP*CP*GP*CP*TP*AP*CP*C)-3'); DNA…
Ligands: PIQ

Structure

solution nmr · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA (5'-D(CPCPAPTPCPGPCPTPAPCP*C)-3')	dna	11	—	—
B	DNA (5'-D(GPGPTPAPGPCPGPAPTPGP*G)-3')	dna	11	—	—

Ligands and binding sites

PIQ · 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine · ligand · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

A–B · 488 Å² buried · 44 hydrogen bonds · nucleic-nucleic

Modifications

Observed in the structure: 1 covalent (covalent ligand).

Compared structures

1HZ0 · NMR structure of the 2-amino-1-methyl-6-PHENYLIMIDAZO[4,5-B]PYRIDINE (phip)… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 1HZ0 · PDBe 1HZ0

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