MolNFT v1 · #95137 · protein
Crystal structure of uncleaved thnt T282A
4IHE · Thnt protein: “Crystal structure of uncleaved thnt T282A”. X-ray diffraction, 8 pockets (best druggability 0.50). MolNFT v1 #95137 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4IHE
- Type
- protein
- Length
- 718 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Thnt protein
- EC
- 3.5.1.92
- UniProt
- Q83XN4
- Pockets
- 8 · best druggability 0.50
Structure
x-ray diffraction · 2 distinct chains · 33% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Thnt protein (EC 3.5.1.92) | protein | 358 | 33% helix, 26% strand | Q83XN4 |
| B | Thnt protein (EC 3.5.1.92) | protein | 360 | 33% helix, 26% strand | Q83XN4 |
Pockets
8 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 185 | 0.50 | 0.77 | 38 | empty |
| 2 | 147 | 0.46 | 0.77 | 33 | empty |
| 3 | 142 | 0.44 | 0.76 | 24 | empty |
| 4 | 118 | 0.43 | 0.77 | 20 | empty |
| 5 | 101 | 0.40 | 0.77 | 18 | empty |
Interfaces
1 interface between chains.
- A–B · 1338 Ų buried · 25 hydrogen bonds · protein-protein
Compared structures
- 4IHE · Crystal Structure of Uncleaved ThnT T282A · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q83XN4
- Elsewhere: RCSB PDB 4IHE · PDBe 4IHE · UniProt Q83XN4
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