MolNFT v1 · #9493 · protein
Crystal structure of an active site mutant of methanobacterium thermoautotrophicum nicotinamide mononucleotide adenylyltransferase
1HYB: “Crystal structure of an active site mutant of methanobacterium thermoautotrophicum nicotinamide…”. X-ray diffraction, 2 ligands (NMN, SO4), 1 pocket (best druggability 0.57). MolNFT v1 #9493 on GenesisL1: 3D structure, binding sites…
- PDB
- 1HYB
- Type
- protein
- Length
- 161 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Nicotinamide mononucleotide adenylyltransferase
- EC
- 2.7.7.1
- UniProt
- O26253
- Ligands
- NMN, SO4
- Pockets
- 1 · best druggability 0.57
Structure
x-ray diffraction · 1 distinct chain · 50% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nicotinamide mononucleotide adenylyltransferase (EC 2.7.7.1) | protein | 161 | 50% helix, 14% strand | O26253 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 277 | 0.57 | 0.77 | 32 | SO4, NMN |
Compared structures
- 1HYB · Crystal structure of an active site mutant of methanobacterium thermoautotrophicum… · the same entry in another collection · chain A against A, TM-score 1.00
- O26253 · AlphaFold monomer V2.0 prediction for nicotinamide-nucleotide adenylyltransferase (O26253) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O26253
- Elsewhere: RCSB PDB 1HYB · PDBe 1HYB · UniProt O26253
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.