MolNFT v1 · #94774 · protein

Crystal structure of PAR3-ntd domain

4I6P · Partitioning defective 3 homolog: “Crystal structure of PAR3-ntd domain”. X-ray diffraction, 1 pocket (best druggability 0.32). MolNFT v1 #94774 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4I6P
Type: protein
Length: 166 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Partitioning defective 3 homolog
UniProt: Q9Z340
Pockets: 1 · best druggability 0.32

Structure

x-ray diffraction · 2 distinct chains · 22% helix, 40% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Partitioning defective 3 homolog	protein	84	24% helix, 39% strand	Q9Z340
B	Partitioning defective 3 homolog	protein	82	20% helix, 40% strand	Q9Z340

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	59	0.32	0.76	20	empty

Interfaces

1 interface between chains.

A–B · 573 Å² buried · 13 hydrogen bonds · protein-protein

Compared structures

4I6P · Crystal structure of Par3-NTD domain · the same entry in another collection · chain A against A, TM-score 1.00
Q9Z340 · AlphaFold monomer V2.0 prediction for partitioning defective 3 homolog (Q9Z340) · a predicted model of the same protein · chain B against A, TM-score 0.94

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9Z340
Elsewhere: RCSB PDB 4I6P · PDBe 4I6P · UniProt Q9Z340

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