MolNFT v1 · #9473 · protein

1.8 ångströms crystal structure of the C-terminal domain of rabbit serum hemopexin

1HXN: “1.8 ångströms crystal structure of the C-terminal domain of rabbit serum hemopexin”. X-ray diffraction, 3 ligands (NA, PO4, CL), 2 pockets (best druggability 0.46). MolNFT v1 #9473 on GenesisL1: 3D structure, binding sites and…

PDB: 1HXN
Type: protein
Length: 210 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Hemopexin
UniProt: P20058
Ligands: NA, PO4, CL
Pockets: 2 · best druggability 0.46

Structure

x-ray diffraction · 1 distinct chain · 13% helix, 34% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Hemopexin	protein	210	13% helix, 34% strand	P20058

Ligands and binding sites

NA · Sodium ion · metal · 2 copies · chains A
PO4 · Phosphate ion · ion · chains A
CL · Chloride ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	110	0.46	0.79	24	PO4
2	64	0.31	0.75	16	empty

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

1HXN · 1.8 ångströms crystal structure of the C-terminal domain of rabbit serum hemopexin · the same entry in another collection · chain A against A, TM-score 1.00
P20058 · AlphaFold monomer V2.0 prediction for hemopexin (P20058) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P20058
Elsewhere: RCSB PDB 1HXN · PDBe 1HXN · UniProt P20058

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