MolNFT v1 · #94623 · protein + DNA
Binary complex of mouse tdt with ssdna and zn++
4I28 · DNA nucleotidylexotransferase: “Binary complex of mouse tdt with ssdna and zn++”. X-ray diffraction, 3 ligands (NA, ZN, MG), 1 pocket (best druggability 0.70). MolNFT v1 #94623 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 4I28
- Type
- protein + DNA
- Length
- 357 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- DNA nucleotidylexotransferase; 5'-D(*AP*AP*AP*AP*A)-3'
- EC
- 2.7.7.31
- UniProt
- P09838
- Ligands
- NA, ZN, MG
- Pockets
- 1 · best druggability 0.70
Structure
x-ray diffraction · 2 distinct chains · 50% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA nucleotidylexotransferase (EC 2.7.7.31) | protein | 352 | 50% helix, 15% strand | P09838 |
| C | 5'-D(*AP*AP*AP*AP*A)-3' | dna | 5 | — | — |
Ligands and binding sites
- NA · Sodium ion · metal · chains A, C
- ZN · Zinc ion · metal · chains A, C
- MG · Magnesium ion · metal · chains A, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1043 | 0.70 | 0.75 | 69 | MG |
Interfaces
1 interface between chains.
- A–C · 627 Ų buried · 17 hydrogen bonds · protein-nucleic
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P09838
- Elsewhere: RCSB PDB 4I28 · PDBe 4I28 · UniProt P09838
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.