MolNFT v1 · #94571 · protein

Nucleoporin elys (AA1-494), mus musculus

4I0O · Protein elys: “Nucleoporin elys (AA1-494), mus musculus”. X-ray diffraction, 2 pockets (best druggability 0.78). MolNFT v1 #94571 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4I0O
Type: protein
Length: 463 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein elys
UniProt: Q8CJF7
Pockets: 2 · best druggability 0.78

Structure

x-ray diffraction · 1 distinct chain · 12% helix, 49% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein elys	protein	463	12% helix, 49% strand	Q8CJF7

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	991	0.78	0.80	72	empty
2	53	0.36	0.79	13	empty

Modifications

Observed in the structure: 4 modified (engineered).

Compared structures

4I0O · Nucleoporin ELYS (aa1-494), Mus musculus · the same entry in another collection · chain A against A, TM-score 1.00
Q8CJF7 · AlphaFold monomer V2.0 prediction for protein elys (Q8CJF7) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8CJF7
Elsewhere: RCSB PDB 4I0O · PDBe 4I0O · UniProt Q8CJF7

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