MolNFT v1 · #94514 · protein
Crystal structure of a DUF3887 family protein (RUMGNA_01855) from ruminococcus gnavus atcc 29149 at 2.25 a resolution
4HYZ · Uncharacterized protein: “Crystal structure of a DUF3887 family protein (RUMGNA_01855) from ruminococcus gnavus atcc 29149 at 2.25 a…”. X-ray diffraction, 2 ligands (SO4, CL), 3 pockets (best druggability 0.54). MolNFT v1 #94514 on…
- PDB
- 4HYZ
- Type
- protein
- Length
- 228 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Uncharacterized protein
- UniProt
- A7B2S7
- Ligands
- SO4, CL
- Pockets
- 3 · best druggability 0.54
Structure
x-ray diffraction · 1 distinct chain · 32% helix, 39% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Uncharacterized protein | protein | 114 | 32% helix, 39% strand | A7B2S7 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 6 copies · chains A, B
- CL · Chloride ion · ion · 6 copies · chains A, B
- GOL · Glycerol · additive · 8 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 282 | 0.54 | 0.75 | 28 | CL, GOL, SO4 |
| 2 | 55 | 0.29 | 0.75 | 14 | empty |
| 3 | 54 | 0.27 | 0.74 | 17 | GOL |
Interfaces
1 interface between chains.
- A–B · 130 Ų buried · 0 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 6 modified (engineered).
Compared structures
- 4HYZ · Crystal structure of a DUF3887 family protein (RUMGNA_01855) from Ruminococcus gnavus… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A7B2S7
- Elsewhere: RCSB PDB 4HYZ · PDBe 4HYZ · UniProt A7B2S7
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