MolNFT v1 · #94502 · protein

X-ray crystal structure of thermotoga maritima fliy

4HYN · Chec, inhibitor of mcp methylation / flin fusion protein: “X-ray crystal structure of thermotoga maritima fliy”. X-ray diffraction, 4 pockets (best druggability 0.79). MolNFT v1 #94502 on GenesisL1: 3D structure, binding sites and…

PDB: 4HYN
Type: protein
Length: 400 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Chec, inhibitor of mcp methylation / flin fusion protein
UniProt: G4FDE4
Pockets: 4 · best druggability 0.79

Structure

x-ray diffraction · 2 distinct chains · 42% helix, 29% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Chec, inhibitor of mcp methylation / flin fusion protein	protein	202	42% helix, 28% strand	G4FDE4
B	Chec, inhibitor of mcp methylation / flin fusion protein	protein	198	42% helix, 29% strand	G4FDE4

Pockets

4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	122	0.79	0.97	28	empty
2	67	0.75	0.98	21	empty
3	126	0.56	0.83	25	empty
4	55	0.31	0.76	18	empty

Interfaces

1 interface between chains.

A–B · 460 Å² buried · 6 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 24 modified (engineered).

Compared structures

4HYN · X-ray crystal structure of Thermotoga maritima FliY · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt G4FDE4
Elsewhere: RCSB PDB 4HYN · PDBe 4HYN · UniProt G4FDE4

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