MolNFT v1 · #94424 · protein
Crystal structure of ATBAG2
4HWD · Bag family molecular chaperone regulator 2: “Crystal structure of ATBAG2”. X-ray diffraction, 4 pockets (best druggability 0.51). MolNFT v1 #94424 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4HWD
- Type
- protein
- Length
- 261 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Bag family molecular chaperone regulator 2
- UniProt
- Q0WPX7
- Pockets
- 4 · best druggability 0.51
Structure
x-ray diffraction · 3 distinct chains · 85% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| D | Bag family molecular chaperone regulator 2 | protein | 90 | 86% helix, 0% strand | Q0WPX7 |
| A | Bag family molecular chaperone regulator 2 | protein | 86 | 85% helix, 0% strand | Q0WPX7 |
| B | Bag family molecular chaperone regulator 2 | protein | 85 | 85% helix, 0% strand | Q0WPX7 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 138 | 0.51 | 0.80 | 20 | empty |
| 2 | 129 | 0.39 | 0.74 | 16 | empty |
| 3 | 82 | 0.38 | 0.77 | 15 | empty |
| 4 | 67 | 0.28 | 0.73 | 17 | empty |
Interfaces
2 interfaces between chains.
- D–A · 551 Ų buried · 6 hydrogen bonds · protein-protein
- D–B · 410 Ų buried · 4 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q0WPX7
- Elsewhere: RCSB PDB 4HWD · PDBe 4HWD · UniProt Q0WPX7
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