MolNFT v1 · #94411 · protein

Crystal structure of SSO10A-2, a DNA-binding protein from sulfolobus solfataricus

4HW0 · DNA-binding protein SSO10A-2: “Crystal structure of SSO10A-2, a DNA-binding protein from sulfolobus solfataricus”. X-ray diffraction, 1 pocket (best druggability 0.30). MolNFT v1 #94411 on GenesisL1: 3D structure, binding sites and…

PDB: 4HW0
Type: protein
Length: 286 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: DNA-binding protein SSO10A-2
UniProt: Q97V10
Pockets: 1 · best druggability 0.30

Structure

x-ray diffraction · 3 distinct chains · 63% helix, 14% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA-binding protein SSO10A-2	protein	98	61% helix, 14% strand	Q97V10
B	DNA-binding protein SSO10A-2	protein	95	63% helix, 15% strand	Q97V10
C	DNA-binding protein SSO10A-2	protein	93	66% helix, 14% strand	Q97V10

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	57	0.30	0.75	13	empty

Interfaces

2 interfaces between chains.

B–C · 1122 Å² buried · 4 hydrogen bonds · protein-protein
A–B · 199 Å² buried · 0 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 6 modified, 3 disulfide (engineered, disulfide).

Compared structures

4HW0 · Crystal structure of Sso10a-2, a DNA-binding protein from Sulfolobus solfataricus · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q97V10
Elsewhere: RCSB PDB 4HW0 · PDBe 4HW0 · UniProt Q97V10

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