MolNFT v1 · #94410 · protein
Crystal structure of brucella abortus immunogenic BP26 protein
4HVZ · 26 kda periplasmic immunogenic protein: “Crystal structure of brucella abortus immunogenic BP26 protein”. X-ray diffraction, 8 pockets (best druggability 0.78). MolNFT v1 #94410 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 4HVZ
- Type
- protein
- Length
- 856 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 26 kda periplasmic immunogenic protein
- UniProt
- Q44642
- Pockets
- 8 · best druggability 0.78
Structure
x-ray diffraction · 1 distinct chain · 32% helix, 34% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D | 26 kda periplasmic immunogenic protein | protein | 214 | 32% helix, 34% strand | Q44642 |
Pockets
8 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 813 | 0.78 | 0.82 | 106 | empty |
| 2 | 619 | 0.75 | 0.82 | 67 | empty |
| 3 | 457 | 0.70 | 0.81 | 61 | empty |
| 4 | 219 | 0.56 | 0.79 | 39 | empty |
| 5 | 139 | 0.52 | 0.80 | 27 | empty |
Interfaces
3 interfaces between chains.
- C–D · 2031 Ų buried · 20 hydrogen bonds · protein-protein
- A–B · 1934 Ų buried · 23 hydrogen bonds · protein-protein
- B–C · 1891 Ų buried · 19 hydrogen bonds · protein-protein
Compared structures
- 4HVZ · Crystal structure of brucella abortus immunogenic BP26 protein · the same entry in another collection · chain D against D, TM-score 1.00
- Q44642 · AlphaFold monomer V2.0 prediction for 26 kda periplasmic immunogenic protein (Q44642) · a predicted model of the same protein · chain A against A, TM-score 0.86
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q44642
- Elsewhere: RCSB PDB 4HVZ · PDBe 4HVZ · UniProt Q44642
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