MolNFT v1 · #94360 · protein
Structure of the bacteriophage T4 tail terminator protein, GP15 (C- terminal truncation mutant 1-261).
4HUH · Tail connector protein GP15: “Structure of the bacteriophage T4 tail terminator protein, GP15 (C- terminal truncation mutant 1-261).”. X-ray diffraction, 16 pockets (best druggability 0.70). MolNFT v1 #94360 on GenesisL1: 3D…
- PDB
- 4HUH
- Type
- protein
- Length
- 1,226 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tail connector protein GP15
- UniProt
- P11112
- Pockets
- 16 · best druggability 0.70
Structure
x-ray diffraction · 5 distinct chains · 22% helix, 42% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tail connector protein GP15 | protein | 211 | 24% helix, 40% strand | P11112 |
| B, D | Tail connector protein GP15 | protein | 202 | 22% helix, 42% strand | P11112 |
| C | Tail connector protein GP15 | protein | 202 | 22% helix, 42% strand | P11112 |
| E | Tail connector protein GP15 | protein | 206 | 22% helix, 41% strand | P11112 |
| F | Tail connector protein GP15 | protein | 203 | 22% helix, 42% strand | P11112 |
Pockets
16 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 542 | 0.70 | 0.79 | 58 | empty |
| 2 | 535 | 0.69 | 0.79 | 58 | empty |
| 3 | 575 | 0.69 | 0.78 | 57 | empty |
| 4 | 518 | 0.68 | 0.78 | 58 | empty |
| 5 | 347 | 0.63 | 0.79 | 28 | empty |
Interfaces
6 interfaces between chains.
- C–D · 1195 Ų buried · 12 hydrogen bonds · protein-protein
- B–C · 1184 Ų buried · 13 hydrogen bonds · protein-protein
- A–B · 1178 Ų buried · 12 hydrogen bonds · protein-protein
- E–F · 1175 Ų buried · 11 hydrogen bonds · protein-protein
- D–E · 1173 Ų buried · 13 hydrogen bonds · protein-protein
Compared structures
- 4HUH · Structure of the bacteriophage T4 tail terminator protein, gp15 (C-terminal truncation… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P11112
- Elsewhere: RCSB PDB 4HUH · PDBe 4HUH · UniProt P11112
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