MolNFT v1 · #94139 · protein

Crystal structure of human catenin-beta-like 1 56 kda fragment

4HNM · Beta-catenin-like protein 1: “Crystal structure of human catenin-beta-like 1 56 kda fragment”. X-ray diffraction, 6 pockets (best druggability 0.61). MolNFT v1 #94139 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4HNM
Type: protein
Length: 484 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Beta-catenin-like protein 1
UniProt: Q8WYA6
Pockets: 6 · best druggability 0.61

Structure

x-ray diffraction · 1 distinct chain · 76% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Beta-catenin-like protein 1	protein	484	76% helix, 0% strand	Q8WYA6

Pockets

6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	376	0.61	0.77	34	empty
2	73	0.59	0.89	19	empty
3	53	0.34	0.78	12	empty
4	71	0.32	0.74	18	empty
5	51	0.30	0.76	12	empty

Modifications

Observed in the structure: 19 modified (engineered).

Compared structures

4HNM · Crystal structure of human catenin-beta-like 1 56 kDa fragment · the same entry in another collection · chain A against A, TM-score 1.00
Q8WYA6 · AlphaFold monomer V2.0 prediction for beta-catenin-like protein 1 (Q8WYA6) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8WYA6
Elsewhere: RCSB PDB 4HNM · PDBe 4HNM · UniProt Q8WYA6

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