MolNFT v1 · #93983 · protein
Crystal structure of rhodobacter sphaeroides lov protein
4HJ3: “Crystal structure of rhodobacter sphaeroides lov protein”. X-ray diffraction, 1 ligand (FMN), 4 pockets (best druggability 0.73). MolNFT v1 #93983 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4HJ3
- Type
- protein
- Length
- 351 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Lov protein
- Ligands
- FMN
- Pockets
- 4 · best druggability 0.73
Structure
x-ray diffraction · 2 distinct chains · 45% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Lov protein | protein | 175 | 45% helix, 21% strand | — |
| B | Lov protein | protein | 176 | 45% helix, 22% strand | — |
Ligands and binding sites
- FMN · Flavin mononucleotide · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 177 | 0.73 | 0.90 | 24 | FMN |
| 2 | 173 | 0.73 | 0.90 | 22 | FMN |
| 3 | 94 | 0.56 | 0.85 | 18 | empty |
| 4 | 79 | 0.48 | 0.83 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 1187 Ų buried · 14 hydrogen bonds · protein-protein
Compared structures
- 4HJ3 · Crystal Structure of Rhodobacter Sphaeroides LOV protein · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 4HJ3 · PDBe 4HJ3
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.