MolNFT v1 · #93958 · protein
Anti-streptococcus pneumoniae 23F Fab 023.102
4HIE: “Anti-streptococcus pneumoniae 23F Fab 023.102”. X-ray diffraction, 3 pockets (best druggability 0.55). MolNFT v1 #93958 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4HIE
- Type
- protein
- Length
- 418 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Fab 023.102; Antibody 023.102
- Pockets
- 3 · best druggability 0.55
Structure
x-ray diffraction · 2 distinct chains · 6% helix, 51% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Fab 023.102 | protein | 212 | 5% helix, 50% strand | — |
| B | Antibody 023.102 | protein | 206 | 6% helix, 52% strand | — |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 354 | 0.55 | 0.74 | 45 | empty |
| 2 | 80 | 0.36 | 0.76 | 19 | empty |
| 3 | 85 | 0.35 | 0.75 | 19 | empty |
Interfaces
1 interface between chains.
- A–B · 1853 Ų buried · 18 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 disulfide (disulfide).
Compared structures
- 4HIE · Anti-Streptococcus pneumoniae 23F Fab 023.102 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 4HIE · PDBe 4HIE
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.