MolNFT v1 · #93833 · protein
Crystal structure of appa schic domain from rb. sphaeroides
4HEH · Appa protein: “Crystal structure of appa schic domain from rb. sphaeroides”. X-ray diffraction, 7 pockets (best druggability 0.63). MolNFT v1 #93833 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4HEH
- Type
- protein
- Length
- 426 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Appa protein
- UniProt
- Q53119
- Pockets
- 7 · best druggability 0.63
Structure
x-ray diffraction · 1 distinct chain · 58% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Appa protein | protein | 213 | 58% helix, 9% strand | Q53119 |
Pockets
7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 80 | 0.63 | 0.91 | 21 | empty |
| 2 | 91 | 0.63 | 0.89 | 22 | empty |
| 3 | 138 | 0.53 | 0.81 | 33 | empty |
| 4 | 97 | 0.52 | 0.83 | 21 | empty |
| 5 | 100 | 0.46 | 0.80 | 23 | empty |
Interfaces
1 interface between chains.
- A–B · 1171 Ų buried · 12 hydrogen bonds · protein-protein
Compared structures
- 4HEH · Crystal structure of AppA SCHIC domain from Rb. sphaeroides · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q53119
- Elsewhere: RCSB PDB 4HEH · PDBe 4HEH · UniProt Q53119
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