MolNFT v1 · #93788 · protein

Crystal structure of squalene synthase hpnc from alicyclobacillus acidocaldarius

4HD1: “Crystal structure of squalene synthase hpnc from alicyclobacillus acidocaldarius”. X-ray diffraction, 1 ligand (SO4), 1 pocket (best druggability 0.74). MolNFT v1 #93788 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4HD1
Type: protein
Length: 263 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Squalene synthase hpnc
EC: 2.5.1.32
UniProt: C8WSG3
Ligands: SO4
Pockets: 1 · best druggability 0.74

Structure

x-ray diffraction · 1 distinct chain · 73% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Squalene synthase hpnc (EC 2.5.1.32)	protein	263	73% helix, 1% strand	C8WSG3

Ligands and binding sites

SO4 · Sulfate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	865	0.74	0.78	49	empty

Modifications

Observed in the structure: 4 modified (engineered).

Compared structures

4HD1 · Crystal structure of squalene synthase HpnC from Alicyclobacillus acidocaldarius · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt C8WSG3
Elsewhere: RCSB PDB 4HD1 · PDBe 4HD1 · UniProt C8WSG3

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.