MolNFT v1 · #93738 · protein

Structure of the aldose reductase from schistosoma japonicum

4HBK · Aldo-keto reductase family 1, member B4 (aldose reductase): “Structure of the aldose reductase from schistosoma japonicum”. X-ray diffraction, 1 pocket (best druggability 0.48). MolNFT v1 #93738 on GenesisL1: 3D structure, binding…

PDB: 4HBK
Type: protein
Length: 301 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Aldo-keto reductase family 1, member B4 (aldose reductase)
EC: 1.1.1.21
UniProt: Q5DD64
Pockets: 1 · best druggability 0.48

Structure

x-ray diffraction · 1 distinct chain · 42% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Aldo-keto reductase family 1, member B4 (aldose reductase) (EC 1.1.1.21)	protein	301	42% helix, 16% strand	Q5DD64

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	176	0.48	0.76	30	empty

Compared structures

4HBK · Structure of the Aldose Reductase from Schistosoma japonicum · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5DD64
Elsewhere: RCSB PDB 4HBK · PDBe 4HBK · UniProt Q5DD64

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