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MolNFT v1 · #93500 · protein

Crystal structure of the C-terminal domain of drosophila melanogaster zucchini

4H4A · Mitochondrial cardiolipin hydrolase: “Crystal structure of the C-terminal domain of drosophila melanogaster zucchini”. X-ray diffraction, 1 pocket (best druggability 0.38). MolNFT v1 #93500 on GenesisL1: 3D structure, binding sites…

PDB
4H4A
Type
protein
Length
151 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Mitochondrial cardiolipin hydrolase
EC
3.1.4.-
UniProt
Q9VKD7
Pockets
1 · best druggability 0.38

Structure

x-ray diffraction · 1 distinct chain · 43% helix, 19% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AMitochondrial cardiolipin hydrolase (EC 3.1.4.-)protein15143% helix, 19% strandQ9VKD7

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1990.380.7622empty

Modifications

Observed in the structure: 5 modified (engineered).

Compared structures

  • 4H4A · Crystal structure of the C-terminal domain of Drosophila melanogaster Zucchini · the same entry in another collection · chain A against A, TM-score 1.00
  • Q9VKD7 · AlphaFold monomer V2.0 prediction for mitochondrial cardiolipin hydrolase (Q9VKD7) · a predicted model of the same protein · chain A against A, TM-score 0.92

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