MolNFT v1 · #93209 · protein
Putative L-cystine ABC transporter from listeria monocytogenes
4GVO · LMO2349 protein: “Putative L-cystine ABC transporter from listeria monocytogenes”. X-ray diffraction, 4 ligands (HIS, CSX, NA), 4 pockets (best druggability 0.82). MolNFT v1 #93209 on GenesisL1: 3D structure, binding sites and…
- PDB
- 4GVO
- Type
- protein
- Length
- 472 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- LMO2349 protein
- UniProt
- Q8Y4T3
- Ligands
- HIS, CSX, NA, CL
- Pockets
- 4 · best druggability 0.82
Structure
x-ray diffraction · 1 distinct chain · 38% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | LMO2349 protein | protein | 236 | 38% helix, 25% strand | Q8Y4T3 |
Ligands and binding sites
- HIS · Histidine · ligand · 2 copies · chains A, B
- CSX · S-oxy cysteine · ligand · 2 copies · chains A, B
- NA · Sodium ion · metal · 2 copies · chains A, B
- CL · Chloride ion · ion · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 372 | 0.82 | 0.91 | 47 | HIS, CSX |
| 2 | 475 | 0.74 | 0.83 | 45 | HIS, CSX |
| 3 | 780 | 0.74 | 0.79 | 63 | empty |
| 4 | 58 | 0.30 | 0.75 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 343 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 4GVO · Putative L-Cystine ABC transporter from Listeria monocytogenes · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8Y4T3
- Elsewhere: RCSB PDB 4GVO · PDBe 4GVO · UniProt Q8Y4T3
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