MolNFT v1 · #92845 · protein

Putative SPERMIDINE/PUTRESCINE ABC transporter from listeria monocytogenes

4GL0 · LMO0810 protein: “Putative SPERMIDINE/PUTRESCINE ABC transporter from listeria monocytogenes”. X-ray diffraction, 3 pockets (best druggability 0.55). MolNFT v1 #92845 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4GL0
Type: protein
Length: 322 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: LMO0810 protein
UniProt: Q8Y8T4
Pockets: 3 · best druggability 0.55

Structure

x-ray diffraction · 1 distinct chain · 47% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	LMO0810 protein	protein	322	47% helix, 20% strand	Q8Y8T4

Ligands and binding sites

EDO · 1,2-ethanediol · additive · 6 copies · chains A
PG4 · Tetraethylene glycol · additive · 2 copies · chains A
PGE · Triethylene glycol · additive · chains A
PEG · Di(hydroxyethyl)ether · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	96	0.55	0.85	32	PGE
2	72	0.38	0.78	18	empty
3	70	0.32	0.74	14	empty

Modifications

Observed in the structure: 15 modified (engineered).

Compared structures

4GL0 · Putative spermidine/putrescine ABC transporter from Listeria monocytogenes · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8Y8T4
Elsewhere: RCSB PDB 4GL0 · PDBe 4GL0 · UniProt Q8Y8T4

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